Hattori M, Yabuuchi A, Tanaka H, Kawara T, Wang H, Inoue K, Shiozawa S, Komai K.
Expression of ASC splice variant found in Japanese patients with palindromic rheumatism is regulated by rs8056505 single nucleotide polymorphism and interleukin-1 beta. Asian Pac J Allergy Immunol Online ahead of print.
Hayashi S, Maeda T, Matsubara T, Fukuda K, Funahashi K, Hashimoto M, Tsumiyama K, Kamenaga T, Takashima Y, Matsumoto T, Tachibana S, Kuroda R.
Comparison of the inhibitory effect of tocilizumab and etanercept on the progression of joint erosion in rheumatoid arthritis treatment. Sci Rep 12:17524, 2022.
Hashimoto M, Funahashi K, Tsumiyama K, Takashima Y, Maeda T, Fukuda K, Hayashi S, Kuroda R, Matsubara T. OASL rs10774580 SNP is associated with Herpes Zoster infection in rheumatoid arthritis. Rheumatology: Current Research 12:1000312, 2022.
Suganuma Y, Tanaka H, Kawase A, Kishida A, Yamaguchi M, Yabuuchi A, Inoue K, Shiozawa S, Komai K.
Expression of a PYCARD/ASC variant lacking exon 2 in Japanese patients with palindromic rheumatism increases interleukin-1β secretion. Asian Pac J Allergy Immunol 40:81-86, 2022.
Shiozawa S, Tsumiyama K, Miyazaki Y, Uto K, Sakurai K, Nakashima T, Matsuyama H, Doi A, Tarui M, Izumikawa M, Kimura M, Fujita Y, Satonaka C, Horiuchi T, Matsubara T, Oribe M, Yamane T, Kagawa H, Li QZ, Mizuno K, Mukai Y, Murakami K, Enya T, Tsukimoto S, Hakata Y, Miyazawa M, Shiozawa K.
DOCK8-expressing T follicular helper cells newly generated beyond self-organized criticality cause systemic lupus erythematosus. iScience 25:103537, 2021.
Akiyama C, Tsumiyama K, Uchimura C, Honda E, Miyazaki Y, Sakurai K, Miura Y, Hashiramoto A, Felsher DW, Shiozawa S.
Conditional Upregulation of IFN-α Alone Is Sufficient to Induce Systemic Lupus Erythematosus. J Immunol 203:835-843, 2019.
Motomura H, Seki S, Shiozawa S, Aikawa Y, Nogami M, Kimura T.
A selective c-Fos/AP-1 inhibitor prevents cartilage destruction and subsequent osteophyte formation. Biochem Biophys Res Commun 497:756-761, 2018.
Hashiramoto A, Konishi Y, Murayama K, Kawasaki H, Yoshida K, Tsumiyama K, Tanaka K, Mizuhara M, Shiotsuki T, Kitamura H, Komai K, Kimura T, Yagita H, Shiozawa K, Shiozawa S.
A variant of death-receptor 3 associated with rheumatoid arthritis interferes with apoptosis-induction of T cell. J Biol Chem 293:1933-1943, 2018.
Makino H, Seki S, Yahara Y, Shiozawa S, Aikawa Y, Motomura H, Nogami M, Watanabe K, Sainoh T, Ito H, Tsumaki N, Kawaguchi Y, Yamazaki M, Kimura T.
A selective inhibition of c-Fos/activator protein-1 as a potential therapeutic target for intervertebral disc degeneration and associated pain. Sci Rep 7:16983, 2017.
Harada S, Sakai R, Hirano F, Miyasaka N, Harigai M, REAL Study Group, Shiozawa S.
Association between medications and herpes zoster in Japanese patients with rheumatoid arthritis: a 5-year prospective cohort study. J Rheumatol 44:988-995, 2017.
Takahashi R, Nakatsukasa H, Shiozawa S, Yoshimura A.
SOCS1 is a key molecule that prevents regulatory T cell plasticity under inflammatory conditions. J Immunol 199:149-158, 2017.
Kamide D, Yamashita T, Araki K, Tomifuji M, Tanaka Y, Tanaka S, Shiozawa S, Shiotani A.
Selective Activator Protein-1 Inhibitor T-5224 Prevents Lymph Node Metastasis in an Oral Cancer Model. Cancer Sci 107:666-673, 2016.
Shiozawa K, Yamane T, Murata M, Yoshihara R, Tsumiyama K, Imura S , Shiozawa S.
MMP-3 as a predictor for structural remission in RA patients treated with MTX monotherapy. Arthritis Res Ther 18:55, 2016.
Ishida M, Ueki M, Morishita J, Ueno M, Shiozawa S, Maekawa N.
T-5224, a selective inhibitor of c-Fos/activator protein-1, improves survival by inhibiting serum high mobility group box-1 in lethal lipopolysaccharide-induced acute kidney injury model. J Intensive Care 3:49, 2015.
Yoshida T, Yamashita K, Watanabe M, Koshizuka Y, Kuraya D, Ogura M, Asahi Y, Ono H, Emoto S, Mizukami T, Kobayashi N, Shibasaki S, Tomaru U, Kamachi H, Matsushita M, Shiozawa S, Hirono S, Todo S.
The impact of c-Fos/Activator protein-1 inhibition on allogeneic pancreatic islet transplantation. Am J Transpl 15:2565-2575, 2015.
Verheul MK, Shiozawa K, Levarht EW, Huizinga TW, Toes RE, Trouw LA, Shiozawa S.
Anti-carbamylated protein antibodies in rheumatoid arthritis patients of Asian descent. Rheumatology 54:1930-1932, 2015.
Sakai R, Cho SK, Nanki T, Watanabe K, Yamazaki H, Tanaka M, Koike R, Tanaka Y, Saito K, Hirata S, Amano K, Nagasawa H, Sumida T, Hayashi T, Sugihara T, Dobashi H, Yasuda S, Sawada T, Ezawa K, Ueda A, Fujii T, Migita K, Miyasaka N, Harigai M, REAL Study Group, Shiozawa S.
Head-to-head comparison of the safety of tocilizumab and tumor necrosis factor inhibitors in rheumatoid arthritis (RA) in clinical practice: results from the registry of Japanese RA patients on biologics for long-term safety (REAL) registry. Arthritis Res Ther 17:74, 2015.
Tanaka M, Cho SK, Nanki T, Koike R, Watanabe K, Yamazaki H, Nagasawa H, Amano K, Tanaka Y, Sumida T, Ihata A, Yasuda S, Nakajima A, Sugihara T, Tamura N, Fujii T, Dobashi H, Miura Y, Miyasaka N, Harigai M, REAL Study Group, Shiozawa S.
The risk of serious infection in patients with rheumatoid arthritis treated with tumor necrosis factor inhibitors decreased over time: a report from the registry of Japanese rheumatoid arthritis patients on biologics for long-term safety (REAL) data base. Rheumatol Int 34:1729-1736, 2014.
Cho SK, Sakai R, Nanki T, Koike R, Watanabe K, Yamazaki H, Nagasawa H, Tanaka Y, Nakajima A, Yasuda S, Ihata A, Ezawa K, Won S, Choi CB, Sung YK, Kim TH, Jun JB, Yoo DH, Miyasaka N, Bae SC, Harigai M, REAL Study Group, Shiozawa S.
A comparison of incidence and risk for serious adverse events in rheumatoid arthritis patients with etanercept or adalimumab in Korea and Japan. Mod Rheumatol 24:572-579, 2014.
Tsumiyama K, Shiozawa S.
Induction of de novo autoimmune disease in normal mice upon repeated immunization with antigen. Methods Mol Biol 1142:85-90, 2014.
Shiozawa S, Uto K.
Studies on the T cell receptor (TCR) revision of autoantibody-inducing CD4 T (aiCD4 T) cell. Methods Mol Biol 1142:65-73, 2014.
Miyazaki Y, Shiozawa S. In vivo cell transfer assay to detect autoreactive T cell subsets. Methods Mol Biol 1142:49-53, 2014.
Tsumiyama K, Hashiramoto A, Takimoto M, Tsuji-Kawahara, Miyazawa M, Shiozawa S.
IFNγ-producing effector CD8 T lymphocytes cause immune glomerular injury by recognizing antigen presented as immune complex on target tissue. J Immunol 191:91-96, 2013.
Miyazaki Y, Tsumiyama K, Yamane T, Ito M, Shiozawa S.
Expansion of PD-1-positive effector CD4 T cells in an experimental model of SLE: contribution to the self-organized criticality theory. Kobe J Med Sci 59:E64-E71, 2013.
Miyazaki Y, Tsumiyama K, Yamane T, Ito M, Shiozawa S .
Self-organized criticality theory and the expansion of PD-1 positive effector CD4 T cells: search for autoantibody-inducing CD4 T cells. Front Immunol 4:87, 2013.
Yoshida K, Hashiramoto A, Okano T, Yamane T, Shibanuma N, Shiozawa S.
TNF-α modulates expression of the circadian clock gene Per2 in rheumatoid synovial cells. 2013;42(4):276-80 Scand J Rheumatol 42:276-280, 2013.
Kawasaki Y, Hashiramoto A, Okano T, Sakai Y, Yamane T, Shiozawa K, Shiozawa S, Hashiramoto A.
Shorter disease duration in important for tocilizumab to achieve Boolean remission. Mod Rheumatol 23:1192-1197, 2013.
Yamada K, Ohno T, Aoki H, Semi K, Watanabe A, Moritake H, Shiozawa S, Kunisada T, Kobayashi Y, Toguchida J, Shimizu K, Hara A, Yamada Y.
EWS/ATF1 expression induces sarcomas from neural crest-derived cells in mice. J Clin Invest 123:600-610, 2013.
Yoshida K, Inoue H, Komai K, Yamane T, Hashiramoto A, Shiozawa K, Shiozawa S.
Mixed connective tissue disease (MCTD) is distinct from SLE: study of MICA and HLA gene polymorphism. Tissue Antigens 81:44-45, 2013.
Kameda H, Kanbe K, Sato E, Ueki Y, Saito K, Nagaoka S, Hidaka T, Atsumi T, Tsukano M, Kasama T, Shiozawa S, Tanaka Y, Yamanaka H, Takeuchi T.
A merged presentation of clinical and radiographic data using probability plots in a clinical trial, the JESMR study. Ann Rheum Dis 72:310-312, 2013.
Izuta S, Ueki M, Ueno M, Nishina K, Shiozawa S, Maekawa N.
T-5224, a selective inhibitor of c-Fos/ activator protein-1, attenuates lipopolysaccharide-induced liver injury in mice. Biotechnol Lett 34:2175-2182, 2012.
Miyazaki H, Morishita J, Ueki K, Nishina K, Shiozawa S, Maekawa N.
The effects of a selective inhibitor of c-Fos/activator protein-1 on endotoxin-induced acute kidney injury in mice. BMC Nephrology 13:153, 2012.
Tanaka C, Shiozawa K, Hashiramoto A, Shiozawa S.
A study on the selection of DMARDs for combination therapy with adalimumab. Kobe J Med Sci 58:E41-E50, 2012.
Sakai R, Komano Y, Tanaka M, Nanki T, Koike R, Nagasawa H, Amano K, Nakajima A, Atsumi T, Koike T, Ihata A, Ishigatsubo Y, Saito K, Tanaka Y, Ito S, Sumida T, Tohma S, Tamura N, Fujii T, Hashiramoto A, Nagawasa K, Miyasaka N, Harigai M, REAL Study Group, Shiozawa S.
Time-dependent increased risk for serious infection from continuous use of tumor necrosis factor antagonists over three years in patients with rheumatoid arthritis. Arthritis Care Res 64:1125-1134, 2012.
Shiozawa K, Kawasaki Y, Yamane T, Yoshihara R, Tanaka Y, Uto K, Shiozawa S.
Anticitrullinated protein antibody, but not its titer, is a predictor of radiographic progression and disease activity in rheumatoid arthritis. J Rheumatol 39:694-700, 2012.
Avouac J, Palumbo K, Zerr P, Tomcik M, Dees C, Horn A, Maurere B, Akhmetschina A, Beyer C, Schneider H, Shiozawa S, Distler O, Distler J.
Inhibition of AP-1 signaling abrogates TGF-α mediated activation of fibroblasts and prevents experimental fibrosis. Arthritis Rheum 64:1642-1652, 2012.
Shiozawa S, Tsumiyama K, Miyazaki Y, Uto K, Sakurai K, Nakashima T, Matsuyama H, Doi A, Tarui M, Izumikawa M, Kimura M, Satonaka C, Fujita Y, Horiuchi T, Matsubara T, Oribe M, Yamane T, Kagawa H, Li QZ, Mizuno K, Mukai Y, Murakami K, Enya T, Tsukimoto S, Hakata Y, Miyazawa M, Shiozawa K.
DOCK8-expressing Tfh cells cause SLE: autoimmunity via repeated TCR stimulation by antigen to levels that surpass system’s self-organized criticality.
The 108th Annual Meeting, American Association of Immunologist, May 10-15, 2021, virtual.
Shiozawa S, Tsumiyama K, Miyazaki Y, Sakurai K, Horiuchi T, Oribe M, Yamane T, Kagawa H, Shiozawa K.
Systemic lupus erythematosus (SLE) is caused by expanded DOCK8-positive autoantibody-inducing CD4 T (aiCD4 T) cell.
The 83rd Annual Meeting, The American College of Rheumatology, November 8-13, 2019, Atlanta, USA.
Tsumiyama K, Shiozawa S.
Autoantibody-inducing CD4 T (aiCD4 T) cells which induce systemic lupus erythematosus (SLE) contain follicular helper T cell in addition to the major IL-21-producing CXCR5-ICOShiPD1hi population: Self-Organized Criticality Theory as the cause of SLE.
The 82nd Annual Meeting, The American College of Rheumatology, October 19-24, 2018, Chicago, USA.
Shiozawa S, Tsumiyama K, Miyazaki Y, Sakurai K, Miyazawa M.
Dock8-positive CD4 T cell as autoantibody-inducing CD4 T (aiCD4 T) cell that causes systemic lupus erythematosus (SLE): proof of concept of self-organized criticality theory as a cause of SLE.
The 82nd Annual Meeting, The American College of Rheumatology, October 19-24, 2018, Chicago, USA.
Ribon M, Hervé R, Lemeiter D, Matyja K, Santinon F, Duffy D, Tsumiyama K, Shiozawa S, Boissier MC, Bessis N, Decker P.
Interferon-alpha protects against pain and joint damages in experimental arthritis and is associated with expansion of highly suppressive regulatory T lymphocytes in protected mice and in Tocilizumab-treated rheumatoid arthritis patients.
The 82nd Annual Meeting, The American College of Rheumatology, October 19-24, 2018, Chicago, USA.
Tsumiyama K, Shiozawa S.
Autoantibody-inducing CD4 T (aiCD4 T) cell that induces systemic lupus erythematosus (SLE) includes not only follicular helper T cell but also IL-21-producing CXCR5-ICOShiPD-1hi cell.
The 105th Annual Meeting, American Association of Immunologist, May 4-8, 2018, Austin, USA.
Shiozawa S, Tsumiyama K, Miyazaki Y, Sakurai K, Miyazawa M.
Dock8-positive CD4 T cell as autoantibody-inducing CD4 T (aiCD4 T) cell that causes systemic lupus erythematosus (SLE): proof of concept of self-organized criticality theory as the cause of SLE.
The 105th Annual Meeting, American Association of Immunologist, May 4-8, 2018, Austin, USA.
Sakurai K, Tsumiyama K, Shiozawa S.
The contribution of autoantibody-inducing CD4+ T cell (aiCD4 T cell) help to the B cell maturation and possible autoantibody in systemic lupus erythematosus.
The 105th Annual Meeting, American Association of Immunologist, May 4-8, 2018, Austin, USA.
Ribon M, Matyja K, Herve R, Lemeiter D, Santinon F, Tsumiyama K, Shiozawa S, Boissier MC, Bessis N, Decker P.
Interferon-alpha overexpression triggers an expansion of highly suppressive regulatory T lymphocytes protecting against experimental arthritis.
The 5th Annual Meeting of the International Cytokine & Interferon Society, October 29-November 2, 2017, Kanazawa, Japan.
Ribon M, Matyja K, Hervé R, Lemeiter D, Santinon F, Tsumiyama K, Shiozawa S, Boissier MC, Bessis N, Decker P.
Interferon-alpha overexpression triggers an expansion of highly suppressive regulatory T lymphocytes protecting against experimental arthritis.
The 81st Annual Meeting, The American College of Rheumatology, October 19-24, 2017, San Diego, USA.
Ribon M, Matyja K, Herve R, Lemeiter D, Tsumiyama K, Shiozawa S, Boissier MC, Bessis N, Decker P.
Early mouse interferon-alpha1 overexpression in vivo triggers an expansion of highly suppressive regulatory T lymphocytes protecting against experimental arthritis.
37th European Workshop on Rheumatology Research, March 2-4, 2017, Athens, Greece.
Tsumiyama K, Shiozawa S.
Endoplasmic reticulum stress induces lupus kidney disease by facilitating antigen cross-presentation via the increase of endosomal Sec61.
The 80th Annual Meeting, The American College of Rheumatology, November 11-16, 2016, Washington DC, USA.
Tsumiyama K, Akiyama C,, Miyazaki Y, Miura Y, Hashiramoto A, Shiozawa S.
Double-negative T (DNT) cell over-expressing PD-1 and Helios is responsible for lupus tissue injury in systemic lupus erythematosus (SLE): direct proof that increased interferon alpha (IFNα) expression is sufficient to induce SLE in IFNα-transgenic mice.
The 80th Annual Meeting, The American College of Rheumatology, November 11-16, 2016, Washington DC, USA.
Shiozawa K, Tsumiyama K,, Shiozawa S.
Radiographic progression is less significant in anti-carbamylated antibody-positive patients with rheumatoid arthritis (RA) who were clinically active and under the treatment with biological DMARDs.
The 80th Annual Meeting, The American College of Rheumatology, November 11-16, 2016, Washington DC, USA.
Matyja K, Ribon M, Hervé R, Lemeiter D, Tsumiyama K, Bessis N, Shiozawa S, Boissier MC, Decker P.
Early in vivo induction of mouse interferon-alpha1 overexpression triggers an expansion of highly suppressive regulatory T lymphocytes protecting against experimental arthritis.
The 80th Annual Meeting, The American College of Rheumatology, November 11-16, 2016, Washington DC, USA.
Tsumiyama K, Shiozawa S.
Endosome-to-cytoplasm pathway via Sec61 and proteasomal degradation as an essential component of antigen cross-presentation and the lupus tissue injury in systemic lupus erythematosus (SLE): Extension of our self-organized criticality theory.
The 103rd Annual Meeting, American Association of Immunologist, May 13-17, 2016, Seattle, USA.
Shiozawa S, Miyazaki Y, Tsumiyama K.
Identification of autoantibody-inducing CD4 T cell (aiCD4 T cell) that causes systemic lupus erythematosus (SLE) as DOCK8+CD4 T cell: proof of concept of self-organized criticality theory.
The 79th Annual Meeting, The American College of Rheumatology, November 6-11, 2015, San Francisco, USA.
Shiozawa K, Shiozawa S.
Study of anti-carbamylated protein antibody in the rheumatoid patients who were clinically active and under treatment with biological DMARDs.
The 79th Annual Meeting, The American College of Rheumatology, November 6-11, 2015, San Francisco, USA.
Tsumiyama K, Shiozawa S.
Increase of endosomal Sec61 enhances antigen cross-presentation and induces immune glomerular injury: a novel ‘self-organized criticality theory’ explaining the cause of systemic lupus erythematosus.
The 102nd Annual Meeting, American Association of Immunologist, May 8-12, 2015, New Orleans, USA.
Shiozawa S, Miyazaki Y, Tsumiyama K.
Specifying the autoantibody-inducing CD4 T cell causing systemic lupus erythematosus out of PD-1+CD45RBlo122lo CD4 subpopulation using mass spectrometry.
The 102nd Annual Meeting, American Association of Immunologist, May 8-12, 2015, New Orleans, USA.
Shiozawa K, Yamane T, Murata M, Tanaka C, Yo N, Yoshihara R, Tanaka Y, Tsumiyama K, Shiozawa S.
Good response to methotrexate (MTX) and/or MTX plus adalimumab (ADA): 3yrs study results in patients with rheumatoid arthritis (RA).
The 78th Annual Meeting, The American College of Rheumatology, November 15-19, 2014, Boston, USA.
Shiozawa K, Yamane T, Murata M, Tanaka C, Yo N, Yoshihara R, Tanaka Y, Tsumiyama K, Shiozawa S.
Serum MMP-3 predicts a subgroup with no radiographic progression in rheumatoid arthritis patients with low-dose Methotrexate (MTX) monotherapy.
The 78th Annual Meeting, The American College of Rheumatology, November 15-19, 2014, Boston, USA.
Shiozawa S. Self-organized criticality theory of autoimmunity explaining the cause of SLE.
Special lecture, Claude Bernarde University Lyon, June 5, 2014, Lyon, France.
Shiozawa K, Yamane T, Murata M, Tanaka C, Yo N, Yoshihara R, Tanaka Y, Tsumiyama K, Shiozawa S.
MMP3 predicts a subgroup of rheumatoid patients with structural remission under low-dose methotrexate (MTX) monotherapy.
The 15th Annual Meeting, European League Against Rheumatism, June 11-14, 2014, Paris, France.
Tsumiyama K, Shiozawa S.
Sec61 plays an essential role in facilitating antigen cross-presentation to induce immune glomerular injury: a novel ‘self-organized criticality theory’ explaining cause of SLE.
The 101st Annual Meeting, American Association of Immunologist, May 2-6, 2014, Pittsburgh, USA.
Miyazaki Y, Tsumiyama K, Shiozawa S.
The autoantibody-inducing CD4 T cell (aiCD4 T cell) causing to systemic lupus erythematosus (SLE) belongs to PD-1+CD45RBlo122lo CD4 subpopulation.
The 101st Annual Meeting, American Association of Immunologist, May 2-6, 2014, Pittsburgh, USA.
Miyazaki Y, Tsumiyama K, Shiozawa S.
PD-1+CD45RBlo122lo autoantibody-inducing CD4 T cells (aiCD4 T cells) as a key in the pathogenesis of systemic lupus erythematosus (SLE).
The 77th Annual Meeting, The American College of Rheumatology, October 26-30, 2013, San Diego, USA.
Shiozawa S, Tanaka Y, Yoshihara R, Murata M, Yamane T, Tanaka C, Yo N, Shiozawa K.
MMP3 as a predictor identifying a subgroup of rheumatoid patients who are successfully treated with Methotrexate (MTX) alone but still subject to radiographic progression.
The 77th Annual Meeting, The American College of Rheumatology, October 26-30, 2013, San Diego, USA.
Shiozawa S, Trouw L, Shiozawa K.
Anti-carbamylated protein antibody in Japanese patients with rheumatoid arthritis.
The 77th Annual Meeting, The American College of Rheumatology, October 26-30, 2013, San Diego, USA.
Shiozawa S, Uto K, Tsumiyama K.
Weak TCR signaling due to repeated immunization with antigen is the key for peripheral TCR revision generating aiCD4 T cell: implication to self-organized criticality theory.
The 5th East Asia group of Rheumatology, May 31- June 1, 2013, Seoul, Korea.
Shiozawa S, Tsumiyama K, Miyazaki Y.
Pathogenesis of systemic lupus erythematosus and aiCD4 T cell: new insight on autoimmunity.
The 100th Annual Meeting, American Association of Immunologist, May 3-7, 2013, Honolulu, USA.
Shiozawa S, Uto K, Tsumiyama K.
Weak TCR signaling due to repeated immunization with antigen is the key for peripheral TCR revision generating aiCD4 T cell: a novel self-organized criticality theory.
The 100th Annual Meeting, American Association of Immunologist, May 3-7, 2013, Honolulu, USA.
Tsumiyama K, Shiozawa S.
Antigen cross-presentation via Sec61 is indispensable for the development of lupus nephritis: a novel ‘self-organized criticality theory’ explaining the cause of SLE.
The 100th Annual Meeting, American Association of Immunologist, May 3-7, 2013, Honolulu, USA.
Miyazaki Y, Tsumiyama K, Shiozawa S.
The autoantibody-inducing CD4 T cell causing systemic lupus erythematosus belongs to CCR4+CD45RBlo122lo subpopulation.
The 100th Annual Meeting, American Association of Immunologist, May 3-7, 2013, Honolulu, USA.
Shiozawa S, Miyazaki Y, Tsumiyama K.
Interferon alpha and self-organized criticality theory.
The 76th Annual Meeting, The American College of Rheumatology, November 9-14, 2012, Washington DC, USA.
Tsumiyama K, Shiozawa S.
Sec61 is indispensable for antigen cross-presentation and the development of lupus nephritis: a novel ‘self-organized criticality theory’ explain the cause of systemic lupus erythematosus (SLE).
The 76th Annual Meeting, The American College of Rheumatology, November 9-14, 2012, Washington DC, USA.
Miyazaki Y, Tsumiyama K, Shiozawa S.
The autoantibody-inducing CD4 T cell (aiCD4 T cell) belongs to CCR4+CD45RBlo122lo CD4 subpopulation: a novel ‘self-organized criticality theory’ explains the cause of systemic lupus erythematosus.
The 76th Annual Meeting, The American College of Rheumatology, November 9-14, 2012, Washington DC, USA.
Yoshida K, Hashiramoto A, Okano T, Shibanuma N, Shiozawa S.
TNF alpha modulates the expression of circadian clock gene per2 via D-box motif in the promoter region in rheumatoid synovial cells.
The 76th Annual Meeting, The American College of Rheumatology, November 9-14, 2012, Washington DC, USA.
Date T, Aikawa Y, Yamamoto T, Narita H, Hirono S, Shiozawa S.
Combined effects of a c-Fos/AP-1 inhibitor T-5224 and methotrexate on collagen-induced arthritis in mice.
The 76th Annual Meeting, The American College of Rheumatology, November 9-14, 2012, Washington DC, USA.
Shiozawa S, Tsumiyama K, Miyazaki Y.
Interferon alpha and self-organized criticality theory of autoimmunity.
The 3rd Annual Meeting, European Congress of Immunology, September 5-8, 2012, Glasgow, UK.
Shiozawa S.
Novel self-organized criticality theory of autoimmunity explaining the cause of systemic lupus erythematosus (SLE).
The 16th World Multi-Conference on Systemics, Cybernetics and Informatics, July 17-20, 2012, Oralndo, USA.
Kameda H, Kanbe K, Sato E, Ueki Y, Saito K, Nagaoka S, Hidaka T, Atsumi T, Tsukano M, Kasama T, Shiozawa S, Tanaka Y, Yamanaka H, Takeuchi T.
Continuation/discontinuation of methotrexate and clinical response to etanercept determine the radiographic progression/ repair in patients with rheumatoid arthritis: a subanalysis of 52-week results from the JESMR Study.
The 13th Annual Meeting, European League Against Rheumatism, June 6-9, 2012, Berlin, Germany.
Tsumiyama K, Shiozawa S.
Sec61 is essential for antigen cross-presentation and the development of lupus nephritis.
The 99th Annual Meeting, American Association of Immunologist, May 4-8, 2012, Boston, USA.
Miyazaki Y, Tsumiyama K, Shiozawa S.
CD45RBlo122lo autoantibody-inducing CD4 T cell (aiCD4 T cell) causes systemic lupus erytematosus.
The 99th Annual Meeting, American Association of Immunologist, May 4-8, 2012, Boston, USA.
Komai K, Okuyama T, Sasaki Y, Hashiramoto A, Shiozawa K, Shiozawa S .
Anti-U1C autoantibody interferes with the U1C-mediated splicing of both Ang1 and Tie2 genes in human pulmonary artery smooth muscle cells.
The 99th Annual Meeting, American Association of Immunologist, May 4-8, 2012, Boston, USA.
